Shu-Fen Wung, PhD, MS, RN, ACNP-BC, FAAN

Shu-Fen Wung, PhD, MS, RN, ACNP-BC, FAAN
Associate Professor
520-626-4305
Nursing
Room Number: 
402

Research and Clinical:

Research and Clinical Interest: 
My program of research has focused on clinical and laboratory research in cardiovascular disease, specifically cardiac ischemia and arrhythmias as well as physiologic monitoring.
For more than two decades, I have worked with interdisciplinary teams to develop sensitive and reliable methods to enhance the early diagnosis and management of patients with acute coronary syndromes
, especially in patients with acute posterior wall or right ventricular myocardial infarction.
My research findings support the use of additional posterior leads (V7-V9) along with new electrocardiographic (ECG) criteria developed from my earlier works for the diagnosis of acute posterior wall myocardial ischemia/infarction.
In the laboratory, my research has been on genetic markers of acute coronary syndrome and life-threatening arrhythmias, as well as inflammatory genetic and biomarkers.
As a board certified acute care nurse practitioner, I have extensive clinical and teaching experience with physiologic monitoring and medical devices in the hospital settings and complex acute and chronic illness management.
I have mentored multi-disciplinary pre- and post-doctoral scholars in cardiovascular disease, acute care, genetics/genomics, arrhythmias, patient monitoring, inflammation, and research designs and analysis.
Clinical Expertise: 

 

  • Cardiovascular Nursing

  • Electrocardiology 

  • Phsiologic Monitoring 

  • Cardiovascular Genetics/Genomics 

  • Acute Care

  • Management of Complex Chronic Illness 

Research & Scholarship: 

 

  • The New ECG Criteria for Posterior Myocardial Infarction study 

  • Early Assessment of Patients with Acute Posterior Infarction Using a New ECG Criterion

  • The Genetics and Life-threatening Arrhythmias (GALA) study

  • Prediction of sudden cardiac death using cardiac magnetic resonance imaging

  • Inflammatory Genetic Markers and Acute Coronary Syndrome

  • Family as Context for Clinical Genetics

  • Construction of An Inflammatory Load Index for Assessing Breast Cancer Risk

  • Cardiovascular Risk and Breast Cancer Outcomes

All Funding: 
Funding Source
2012-2013
Construction of An Inflammatory Load Index for Assessing Breast Cancer Risk
The University of Arizona
Co-PI
2010-2012
Cardiovascular Risk and Breast Cancer Outcomes
Oncology Nursing Society Foundation
Co-PI
2008-2009
Prediction of sudden cardiac death using cardiac magnetic resonance Imaging
The University of Arizona
Investigator (PI, Vincent Sorrell)
2007-2008
Genetics and Life-threatening Arrhythmias: A Pilot Study
The University of Arizona
PI
2005-2006
Inflammatory Genetic Markers and Acute Coronary Syndrome, Center on Injury Mechanisms and Related Responses: Genomics Focus
NINR 2P20NR007794-04
PI (Center PI, Ida Ki Moore)
2001-2005
New ECG Criteria for Posterior Myocardial Infarction
NINR RO1 NR08092-01
PI
2001-2002
Family as Context for Clinical Genetics
National Human Genome Research Institute 1R25HG02259-01A1
Content Expert
2000-2002
Early Assessment of patients with Acute Posterior Infarction using a new ECG Criterion.
American Association of Critical Care Nurses
PI
2000-2001
Early Assessment of patients with Acute Posterior Infarction using a new ECG Criterion.
Emergency Nurses Foundation
PI
2000-2001
Early Assessment of patients with Acute Posterior Infarction using a new ECG Criterion.
Sigma Theta Tau International
2000-2001
New ECG criteria for posterior myocardial infarction
The University of Illinois at Chicago
PI
1998-1999
Description of electrocardiographic changes in the posterior leads using PTCA model of posterior myocardial ischemia
University of California San Francisco
PI
1998-1999
Description of electrocardiographic changes in the posterior leads using percutaneous transluminal coronary angioplasty model of posterior myocardial ischemia and its correlation to the site of coronary lesions
Sigma Theta Tau International
PI
Publications: 

* Data-based; # Published with student as the senior author

2015

Wung SF. Twelve-Lead Electrocardiogram. American Association of Critical Care Nurses: AACN Procedure Manual for Critical Care. 7th edition, (in press)

2015

Wung SF, Drew BJ. Extra electrocardiographic (ECG) leads: Right ventricular and left posterior leads. American Association of Critical Care Nurses: AACN Procedure Manual for Critical Care. 7th edition, (in press).

2014

Wung SF.  Atrial fibrillation in elderly: Management strategies to achieve performance measures.  AACN Advanced Critical Care Journal, 25(3), 205-212. 

2014*#

Stoodley L, Wung SF.  Hyperglycemia after cardiac surgery: Improving a quality measure.  AACN Advanced Critical Care Journal.  25(3), 221-227.      

2013

Wung SF, Hickey KT, Taylor JY, Gallek MJ. Cardiovascular genomics. Journal of Nursing Scholarship. 45(1), 60-8.

2012*#

Kozik T, Wung SF. Acquired long QT syndrome: Frequency, Temporal Onset, and Risk Factor Identification in a critical care population. Critical Care Nurse. Oct;32(5):32-41.

2012#

Goodson BL, Wung SF, Archbold K. Obstructive sleep apnea and metabolic syndrome: A synergistic cardiovascular risk factor. Journal of the American Academy of Nurse Practitioners; 24(12), 695-703.

2011#

Wung SF, Lin PC. Shared genomics of type 2 and gestational diabetes mellitus. Annual Review of Nursing Research; 29:227-60.

2010

Calzone KA, Cashion A, Feetham S, Jenkins J, Prows CA, Williams JK, Wung SF. Nurses transforming health Care using genetics and genomics. Nursing Outlook, Jan; 58(1):26-35.

2009#

Kozik TM, Wung SF. Cardiac Arrest from Acquired Long QT Syndrome: A Case Report. Heart & Lung: The Journal of Acute and Critical Care, 38(3), 238-42.

2009

Frazier L, Wung SF, Sparks E, Wood C. Cardiovascular Nursing on Human Genomics: What cardiovascular nurses need to know about congestive heart failure? Prog Cardiovasc Nurs. Sep; 24(3): 80-5.

2008*#

Chang SH, Wung SF, Crogan NL. Improving activities of daily living for nursing home elders in Taiwan. Nursing Research, May-Jun;57(3):191-8.

2008

Wung SF, Aouizerat BE. Candidate genes of the 5-lipoxygenase pathway in acute coronary syndrome: A pilot study. Biological Research for Nursing, Apr;9(4):280-92.

2008

Schwertz D, Aouizerat BE, Wung SF. Gene-environmental interaction in cardiovascular disease. Cardiac Nursing: A Companion to Braunwald's Heart Disease, Saunders Elsevier, St. Louis, 171-187.

2008#

Wung SF, Kozik T. Electrocardiographic evaluation of cardiovascular status. Journal of Cardiovascular Nursing, Mar-Apr;23(2):169-74.

2007*

Wung SF. Differentiation between right and left circumflex coronary artery occlusion Using Noninvasive 18-lead ECG. Am J Critical Care. 16(1), 63-71.

2007#

Chang SH, Crogan NL, Wung SF. The Self-Care Self-Efficacy Enhancement Program for Chinese Nursing Home Elders. Geriatric Nursing; 28(1), 31-36.

2006*

Wung SF, Kulkarni MV, Pulinger CR, Malloy MJ, Kane JP, Aouizerat BE. The lipoprotein lipase gene in combined hyperlipidemia: Evidence of a protective allele depletion. Lipids in Health and Disease. 5(1): 19-26.

2006*#

Wung SF, Kahn D. Quantitative Evaluation of ST Segment Changes on the 18-lead Electrocardiogram During Percutaneous Coronary Interventions. J Electrocardiology, 39(3):275-81.

2005

Wung SF. Electrocardiography in Heart Disease. Resource Manual in Cardiovascular Rehabilitation. p.89-106.

2005#

Brunsvold A., Wung SF, Merkle C. BRCA1 Genetic Mutation and its Link to Ovarian Cancer: Implications for Advanced Practice Nurses. J Am Acad Nurse Pract, 17(12), 518-26.

2004*

Edmonds CR, Wung SF, Husz MJ, Pemberton B. Corneal endothelial cell count in keratoconus patients after contact lens wear. Eye Contact Lens. Jan; 30(1):54-8.

2004

Wung SF, Aouizerat BE. Newly mapped gene for thoracic aortic aneurysm and dissection. J Cardiovasc Nurs. 19(6): 409-416.

2003*

Wung SF, Aouizerat BE. Gender and ethnic differences in a case-control study of dyslipidemia: Using the apolipoprotein A-V gene as an exemplar in cardiovascular genetics. Research and Theory for Nursing Practice. Winter; 17(4):281-99.

2003

Zerwic JJ, Sherry DC, Simmons B, Wung SF. Noncompliance in heart transplantation: A role for the advanced practice nurse. Progress in Cardiovascular Nursing. Summer, 18(3); 141-6.

2002

Wung SF. Genetic advances in coronary artery disease. Medsurg Nursing, 11: 296-300.

2001*

Wung SF, Drew BJ. New electrocardiographic criteria for posterior wall acute myocardial ischemia validated by a percutaneous transluminal coronary angioplasty model of acute myocardial infarction. Am J Cardiology, 87(8):970-4.

2001

Wung SF. Computer-assisted continuous multilead ST segment analysis for clinical research: Methodological issues. Biological Research for Nursing, Oct;3(2):65-77.

2000*

Wung SF, Lux RL, Drew BJ. Thoracic location of the lead with maximal ST segment deviation during right ventricular and posterior wall ischemia: Comparison of right ventricular V3-5R and posterior leads V7-9 with estimated body surface leads. Journal of Electrocardiology, 33 suppl, 167-174.

1999*

Wung SF, Drew BJ. Comparison of 18-lead ECG with selected body surface mapping leads in determining maximally-deviated lead during coronary occlusion. J Electrocardialogy, 32 suppl, 30-37.

1999

Drew BJ, Krucoff MW, Writing Group and Panel of Experts. Multi-Lead ST segment monitoring in patients with acute coronary syndromes suggested clinical practice guideline for healthcare professionals. American Journal of Critical Care, 8(6), 372-386.

1999*

Adams MG, Pelter MM, Wung SF, Taylor C, Drew BJ. Frequency of silent ischemia with ST segment monitoring in the coronary care unit: Are there gender differences? Heart & Lung; 28(2), 81-86.

1999*

Lau K, Wung SF, Adams M, Drew BJ. Frequency of ischemia during intracoronary ultrasound in women with and without coronary artery disease. Critical Care Nurse, 19(5), 48-56.

1999*

Drew BJ, Pelter MM, Wung SF, Taylor C, Evans GT, Foster E. Accuracy of the EASI 12-lead electrocardiogram compared to the standard 12-lead electrocardiogram for diagnosing cardiac abnormalities. J Electrocardialogy, 32 suppl, 38-47.

1998*

Drew BJ, Wung SF, Adams MG, Pelter MM. Bedside diagnosis of myocardial ischemia with ST segment monitoring technology: Measurement issues for real-time clinical decision-making and trial design. Journal of Electrocardiology; 30 suppl, 157-165.

1998*

Drew BJ, Pelter MM, Adams MG, Wung SF, Chou TM, Wolfe CL. 12-lead ST-segment monitoring vs single-lead maximum ST-segment monitoring for detecting ongoing ischemia in patients with unstable coronary syndromes. American Journal of Critical Care; 7, 355-63.

1998*

Pelter MM, Adams MG, Wung SF, Paul SM, Gaskin AL, Drew BJ. Peak time of occurrence of myocardial ischemia in the coronary care unit. American Journal of Critical Care; 7(6), 411-417.

1997*

Drew BJ, Adams MG, Pelter MM, Wung SF, Caldwell MA. Comparison of standard and derived 12-lead electrocardiograms for diagnosis of coronary angioplasty-induced myocardial ischemia. American Journal of Cardiology; 79: 639-644.

1997*

Drew BJ, Adams MG, McEldowney DK, Lau K, Wung SF, Wolfe CL, Ports TA, Chou TM. Frequency, duration, magnitude and consequences of myocardial ischemia during intracoronary ultrasound. American Heart Journal 1997; 134, 474-8.

1996*

Drew BJ, Adams MG, Pelter MM, Wung SF. ST segment monitoring with a derived 12-lead electrocardiogram is superior to routine cardiac care unit monitoring. American Journal of Critical Care; 5: 198-206.

Honors and Awards: 
2008
Excellence in Research Award, Beta Mu Chapter, Sigma Theta Tau International
2005
Outstanding Faculty Award, The University of Arizona Asian American Faculty, Staff and Alumni Association
2005
Fellow, American Academy of Nursing
2002
Fellow, Summer Genetic Institute/National Institute of Health
2001
Fellow, American Heart Association
2000
Martha N. Hill New Investigator Award, American Heart Association
1999
Young Investigator Presenter, International Society of Computerized Electrocardiology
Education: 
Institution/LocationDegreeAttendedField of Study
Georgetown University (NINR Summer Genetics Institute), Washington, DC
Post-Doc
Summer 2002
Genetics
University of California, San Francisco, Ca
Post-MS
2002-2003
Acute Care Nurse Practitioner
University of California, San Francisco, Ca
PhD
1995-1999
Nursing
University of California, San Francisco, Ca
MSN
1993-1995
Cardiovascular Clinical Nurse Specialist
University of Dubuque, Dubuque, Iowa
BSN
1991-1993
Nursing