Thaddeus Pace, PhD

Thaddeus Pace, PhD
Assistant Professor of Nursing
Assistant Professor of Psychiatry
520-626-3520
Nursing
Room Number: 
443

Research and Clinical:

Research and Clinical Interest: 
novel, natural anti-inflammatory compounds such as curcumin to promote health and wellness,
novel contemplative interventions to optimize psychological, inflammatory immune, and endocrine responses to stress,
endocrine and inflammatory immune alterations as a result of adverse early life trauma,
endocrine and immune system changes in stress-related psychiatric illness.
All Funding: 
Funding Source
9/15/14 - 8/31/16
Meriva For Treatment-Induced Inflammation and Fatigue in Women With Breast Cancer (R21CA178603)
National Cancer Institute
PI
12/01/14 - 11/30/15
Cognitively-Based Compassion Training to enhance wellness in Pima County foster care girls
Connie Hillman Family Foundation/ The Women's Foundation of Southern Arizona
co-PI
07/01/12 - 06/30/16
Trauma Biology and Cardiometabolic Risk in African-American Primary Care.
National Institute of Mental Health/ Emory University
site-PI and study co-I
4/01/13 - 3/31/16
Curcuma longa L. in Rheumatoid Arthritis (CLaRA): Clinical Planning Study.
National Center for Complimentary and Alternative Medicine
co-I
Publications: 

(selected, most recent articles from 36 peer-reviewed publications)

Olivera, A., Moore, T.W., Hu, F., Brown, A.P., Sun, A., Liotta, D.C., Snyder, J.P., Yoon, Y., Shim, H., Marcus, A.I., Miller, A.H., and Pace, T.W.W. (2012). Inhibition of the NF-κB signaling pathway by the curcumin analog, 3,5-Bis(2-pyridinylmethylidene)-4-piperidone (EF31): anti-inflammatory and anti-cancer properties. International Immunopharmacology, 12(2), 368-377.

Pace, T.W.W, Negi, L.T., Dodson-Lavelle, B., Ozawa-de Silva, B., Reddy, S.D., Cole, S.P., Danese, A., Craighead, L.W., & Raison, C.L. (2013). Engagement with Cognitively-Based Compassion Training is associated with reduced salivary C-reactive protein from before to after training in foster care program adolescents. Psychoneuroendocrinology, 38(2) 294-299.

Klengel, T., Mehta, D., Anacker, C., Rex-Haffner, M., Pruessner, J.C., Pariante, C.M., Pace, T.W.W., Mercer, K.B., Mayberg, H.S., Bradley, B., Nemeroff, C.B., Holsboer, F., Heim, C.M., Ressler, K.J., Rein, T., & Binder, E.B. (2013). Allele-specific FKBP5 DNA demethylation mediates gene-childhood trauma interactions. Nat Neurosci, Nat Neurosci, 16(1), 33-41.

Corwin, E.J., Guo, Y., Pajer, K., Lowe, N., McCarthy, D., Schmiege, S., Weber, M., Pace, T.W.W., & Stafford, B. (2013). Immune dysregulation and glucocorticoid resistance in minority and low income pregnant women.  Psychoneuroendocrinology, 38 (9), 1786-1796.

Torres, M.A., Pace, T.W.W., Liu, T., Felger, J.C., Mister, D., Doho, G.H., Kohn, J.N., Barsevick, A.M., Long, Q., & Miller, A.H. (2013). Predictors of depression in breast cancer patients treated with radiation: Role of prior chemotherapy and nuclear factor kappa B. Cancer, 119(11), 1951-9.

Divya, M., Torsten, K., Karen, C.N., Smith, A.K., Altmann, A , Pace, T.W.W., Rex-Haffner, M., Loeschner, A., Mariya Gonik, M. , Mercer, K.B. , Bradley, B., Müller-Myhsok, B., Ressler, K.J., & Binder, E.B. (2013). Childhood maltreatment is associated with distinct genomic and epigenetic profiles in posttraumatic stress disorder. Proceedings of the National Academy of Sciences, 110(20), 8302-7.

Smith, A.K., Conneely, K.N., Pace, T.W.W, Mister, D, Felger, J.C., Kilaru, V., Akel, M.J., Vertino, P.M., Miller, A.H., & Torres, M.A. (2014). Epigenetic Changes Associated with Inflammation in Breast Cancer Patients Treated with Chemotherapy. Brain, Behavior, and Immunity, in press.

Krieger S, Sorrells SF, Nickerson M, & Pace T.W.W. (2014). Mechanistic insights into corticosteroids in multiple sclerosis: War horse or chameleon? Clinical Neurology and Neurosurgery, 119:6-16.

 

 

Honors and Awards: 
2012 PopTech (www.poptech.org) Science Fellow
2014 40 Under 40 Honoree, Tucson Hispanic Chamber of Commerce and Arizona Daily Star
Education: 
Institution/LocationDegreeAttendedField of Study
Emory University, Atlanta, GA
Post-Doc
2006
Stress Immunology
University of Colorado at Boulder, Boulder, CO
PhD
2004
Psychology/ Neuroscience
Albright College, Reading, PA
BS
1998
Psychobiology